Karla Kinkade, Ph.D., Assistant Professor of Biology and Public Health, earned her Ph.D. in Microbiology and Immunology at Indiana University School of Medicine. She continued her study as a post-doctoral research scientist at the Herman B Wells Center of Pediatric Research at IUSM studying the structure and function of the phagocyte NADPH-oxidase flavocytochrome b558. She is also certified as a Medical Technologist by the American Society of Clinical Pathologists. Outside of the biology laboratory, Dr. Kinkade is interested in best practices in teaching and learning.
- Ph.D., Microbiology and Immunology, Indiana University School of Medicine, 1997
- B.A., Chemistry, Hanover College, 1985
- BIO 151 General Biology
- BIO 225 Human Anatomy Lab
- BIO 226 General Human Physiology Lab
- BIO 345 Immunology
- PBH 301 Introduction to Epidemiology
Research interests / portfolio
- Analysis of the structure and function of the NADPH-oxidase enzyme
- Immune response to infectious disease
- Integration of faith and science in higher education
- Biberstine-Kinkade, K.J., Yu, L., Stull, N., LeRoy, B., Bennett, S., Cross, A., and Dinauer, M.C. (2002) Mutagenesis of p22phox Histidine 94: A histidine in this position is not required for flavocytchrome b558 function. J. Biol. Chem. 277:30368-74.
- Biberstine-Kinkade, K.J., DeLeo, F.R., Epstein, R.I., LeRoy, B.A., Nauseef, W.M., and Dinauer, M.C. (2001) Heme-ligating histidines in flavocytochrome b558: identification of specific histidines in gp91phox. J. Biol. Chem. 276:31105-12.
- Biberstine-Kinkade, K.J., Yu, L., and Dinauer, M.C. (1999) Mutagenesis of an arginine- and lysine-rich domain in the gp91phox subunit of the phagocyte NADPH-oxidase flavocytochrome b558. J. Biol. Chem. 274:10451-7.
- Yu, L., DeLeo, F.R., Biberstine-Kinkade, K.J., Renee, J., Nauseef, W.M., and Dinauer, M.C. (1999) Biosynthesis of flavocytochrome b588: gp91phox is synthesized as a 65 kDa precursor (p65) in the endoplasmic reticulum. J. Biol. Chem. 274:4364-9.
- Biberstine, K.J., Darr, D.S., and Rosenthal, R.S. (1996) Tolerance to appetite suppression induced by peptidoglycan. Infection and Immunity 64:3641-5.
- Biberstine, K.J., and Rosenthal, R.S. (1994) Peptidoglycan fragments decrease food intake and body weight gain in rats. Infection and Immunity 62:3276-81.